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PhaRNA，LLC是一家總部位于德克薩斯州休斯頓的生物技術(shù)公司，由博士科學家和企業(yè)家創(chuàng)立，他們在藥物產(chǎn)品的設計和應用方面擁有豐富的專業(yè)知識，包括小分子和長（> 150 b）RNA產(chǎn)品。
PhaRNA融合了其創(chuàng)始人的廣泛專業(yè)知識，為基礎(chǔ)和轉(zhuǎn)化研究（包括臨床前，臨床，美容和獸醫(yī)應用）創(chuàng)新RNA的設計和生產(chǎn)。
我們先進的研發(fā)RNA實驗室與我們即將推出的GMP設施相輔相成，這將使我們能夠提供高質(zhì)量的RNA產(chǎn)品，用于IND前期和IND實現(xiàn)的功效和毒性研究。
PhaRNA擁有世界上大的信使RNA模擬（mRNA模擬物）產(chǎn)品檔案，用于研究和開發(fā)活動。PhaRNA的mRNA模擬物代表天然mRNA類似物或修飾的信使RNA（mmRNA）轉(zhuǎn)錄物。PhaRNA，LLC專門設計和合成長（> 150 b）RNA，包括融合和/或Bi- / Poly-cistronic mRNA模擬構(gòu)建體以及長非編碼RNA（lncRNA）產(chǎn)物。
pharna mRNA目錄
Embryonic Stem Cells
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM POU5F1 mRNA | POU domain, class 5, transcription factor 1 | Human | 1000101 | 100 ug | $300 |
| BioCapTM KLF4 mRNA | Krueppel-like factor 4 | Human | 1000201 | 100 ug | $300 |
| BioCapTM SOX2 mRNA | Transcription factor SOX-2 | Human | 1000301 | 100 ug | $300 |
| BioCapTM MYC mRNA | Myc proto-oncogene protein | Human | 1000401 | 100 ug | $300 |
| BioCapTM LIN28A mRNA | Protein lin-28 homolog A | Human | 1000501 | 100 ug | $300 |
| BioCapTM NANOG mRNA | Homeobox protein NANOG | Human | 1000601 | 100 ug | $300 |
Endothelial Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM CDH5 mRNA | Cadherin-5 | Human | 1000701 | 500 ug | $1,550 |
| BioCapTM ETV2 mRNA | ETS translocation variant 2 | Human | 1000801 | 500 ug | $1,550 |
| BioCapTM FLI1 mRNA | Friend leukemia integration 1 transcription factor | Human | 1000901 | 500 ug | $1,550 |
| BioCapTM GATA2 mRNA | Endothelial transcription factor GATA-2 | Human | 1001001 | 500 ug | $1,550 |
| BioCapTM MYB mRNA | Transcriptional activator Myb | Human | 1001101 | 500 ug | $1,550 |
| BioCapTM PECAM1 mRNA | Platelet endothelial cell adhesion molecule | Human | 1001201 | 500 ug | $1,550 |
| BioCapTM RUNX1 mRNA | Runt-related transcription factor 1 | Human | 1001301 | 500 ug | $1,550 |
| BioCapTM VEGFA mRNA | Vascular endothelial growth factor A | Human | 1001401 | 500 ug | $1,550 |
| BioCapTM VEGFB mRNA | Vascular endothelial growth factor B | Human | 1001501 | 500 ug | $1,550 |
Cardiomyocyte and Myocyte Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM GATA4 mRNA | Transcription factor GATA-4 | Human | 1001601 | 500 ug | $1,550 |
| BioCapTM MEF2A mRNA | Myocyte-specific enhancer factor 2A | Human | 1001701 | 500 ug | $1,550 |
| BioCapTM MEF2C mRNA | Myocyte-specific enhancer factor 2C | Human | 1001801 | 500 ug | $1,550 |
| BioCapTM MESP1 mRNA | Mesoderm posterior protein 1 | Human | 1001901 | 500 ug | $1,550 |
| BioCapTM MYOD1 mRNA | Myoblast determination protein 1 | Human | 1002001 | 500 ug | $1,550 |
| BioCapTM TBX5 mRNA | T-box transcription factor TBX5 | Human | 1002101 | 500 ug | $1,550 |
Blood and Hematopoietic Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM GATA1 mRNA | Erythroid transcription factor | Human | 1002201 | 500 ug | $1,550 |
| BioCapTM GATA3 mRNA | Trans-acting T-cell-specific transcription factor GATA-3 | Human | 1002301 | 500 ug | $1,550 |
| BioCapTM GATA4 mRNA | Transcription factor GATA-4 | Human | 1002401 | 500 ug | $1,550 |
| BioCapTM GATA4 G296S Mutant mRNA | Transcription factor GATA-4 G296S Mutant | Human | 1002501 | 500 ug | $1,550 |
Beta Cell Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM MAFA mRNA | Transcription factor MafA | Human | 1002601 | 500 ug | $1,550 |
| BioCapTM NEUROG3 mRNA | Neurogenin-3 | Human | 1002701 | 500 ug | $1,550 |
| BioCapTM PDX1 mRNA | Pancreas/duodenum homeobox protein 1 | Human | 1002801 | 500 ug | $1,550 |
| BioCapTM UL48 mRNA | Tegument protein VP16 | HHV-1 | 1002901 | 500 ug | $1,550 |
Hepatocyte Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM FOXA1 mRNA | Hepatocyte nuclear factor 3-alpha | Human | 1003001 | 500 ug | $1,550 |
| BioCapTM FOXA2 mRNA | Hepatocyte nuclear factor 3-beta | Human | 1003101 | 500 ug | $1,550 |
| BioCapTM FOXA3 mRNA | Hepatocyte nuclear factor 3-gamma | Human | 1003201 | 500 ug | $1,550 |
| BioCapTM HNF1A mRNA | Hepatocyte nuclear factor 1-alpha | Human | 1003301 | 500 ug | $1,550 |
| BioCapTM HNF1B mRNA | Hepatocyte nuclear factor 1-beta | Human | 1003401 | 500 ug | $1,550 |
Neuronal Differentiation Factors
| RNA | ENCODED PROTEIN | SPECIES | CATALOG NUMBER | FROM | PRICE |
|---|---|---|---|---|---|
| BioCapTM ASCL1 mRNA | Achaete-scute homolog 1 | Human | 1003501 | 500 ug | $1,550 |
| BioCapTM FOXA2 mRNA | Hepatocyte nuclear factor 3-beta | Human | 1003601 | 500 ug | $1,550 |
| BioCapTM ISL1 mRNA | Insulin gene enhancer protein ISL-1 | Human | 1003701 | 500 ug | $1,550 |
| BioCapTM LHX3 mRNA | LIM/homeobox protein Lhx3 | Human | 1003801 | 500 ug | $1,550 |
| BioCapTM LMX1A mRNA | LIM homeobox transcription factor 1-alpha | Human | 1003901 | 500 ug | $1,550 |
| BioCapTM MNX1 mRNA | Motor neuron and pancreas homeobox protein 1 | Human | 1004001 | 500 ug | $1,550 |
| BioCapTM NEUROD1 mRNA | Neurogenic differentiation factor 1 | Human | 1004101 | 500 ug | $1,550 |
| BioCapTM NEUROD2 mRNA | Neurogenic differentiation factor 2 | Human | 1004201 | 500 ug | $1,550 |
| BioCapTM NEUROG2 mRNA | Neurogenin-2 | Human | 1004301 | 500 ug | $1,550 |
| BioCapTM POU3F2 mRNA | POU domain, class 3, transcription factor 2 | Human | 1004401 | 500 ug | $1,550 |
| BioCapTM ZIC1 mRNA | Zinc finger protein ZIC 1 | Human | 1004501 | 500 ug | $1,550 |
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