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HMGBIOTECH DISULFIDE HMGB1說明書

更新時間：2024-03-15 點擊次數(shù)：1443

HMGBIOTECH 高遷移率蛋白、質粒、抗體

hmgbiotech HM-120

HMGB 1是細胞核的一個組成部分，在基因組的組織和表達中具有多種功能。HMG生物技術SRL為活躍在這一領域的其他研究人員和公司提供試劑、服務和想法。它還有助于實驗室開發(fā)分析和試劑。

hmgbiotech DISULFIDE HMGB1說明書

hmgbiotech HM-120

HMGB1是一種核蛋白，其由壞死細胞被動釋放，由凋亡細胞保留，并由炎癥細胞主動分泌（Dumitriu等人，HMGB1:從內部引導免疫。Trends Immunol 2005，26:381-7）。HMGB1對生命至關重要：HMGB1基因敲除小鼠出生后不久死亡。

HMGB1作為運動細胞的化學引誘劑和細胞因子的誘導劑的兩種不同活性被歸因于不同的生物化學形式。還原的HMGB1（具有化學引誘活性的形式）被還原；二硫化物HMGB1包含C23和C45之間的二硫鍵（完整注釋：HMGB1C23-C45C106h–Antoine J.等人（2014）。Mol-Med）。

二硫化物HMGB1可誘導單核細胞和其他炎癥細胞產(chǎn)生細胞因子和趨化因子（Venereau等人，2012）。

在結構上，二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測試二硫化物HMGB1刺激細胞因子的能力

HMGBiotech公司熱銷產(chǎn)品

產(chǎn)品名稱	貨號
100 ug Fully reduced HMGB1, LPS free	HM-115
50 ug Fully reduced HMGB1, LPS free	HM-116
100 ug Disulfide HMGB1, LPS free	HM-121
100 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-012
50 ug Disulfide HMGB1, LPS free	HM-122
500 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-013
1 mg HMGB1 for biochemistry	HM-100
2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay	HM-014
250 ug HMGB1 biochemistry	HM-101
25 ug BoxA from HMGB1, LPS-free and tested in migration assay	HM-011
15 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-053
15 ug Fully reduced HMGB1, LPS free	HM-117
10 ug Disulfide HMGB1, LPS free	HM-123
15 ug Non-oxidizable HMGB1, LPS free	HM-133
250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-170
100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-171
50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-172
15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration	HM-173
50 ug HMGB1 15N labelled for Mass Spectrometry	HM-180
5 ug HMGB1 15N labelled for Mass Spectrometry	HM-181
2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-190
500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-191
100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-192
25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay	HM-193
Control cell lysates from Hmgb1 +/+	HM-001
Control cell lysates from Hmgb1 -/-	HM-002
1 mg BoxB from HMGB1, LPS-free and tested in migration assay	HM-050
250 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-051
100 ug BoxB from HMGB1, LPS-free and tested in migration assay	HM-052
500 ug Fully reduced HMGB1, LPS free	HM-114
250 ug Disulfide HMGB1, LPS free	HM-120
500 ug Non-oxidizable HMGB1, LPS free	HM-130
100 ug Non-oxidizable HMGB1, LPS free	HM-131
50 ug Non-oxidizable HMGB1, LPS free	HM-132
500 ug HMGB2, LPS-free and tested in migration assay	HM-151
100 ug HMGB2, LPS-free and tested in migration assay	HM-152
50 ug HMGB2, LPS-free and tested in migration assay	HM-153
Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells	HM-201
Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells	HM-221
Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and	HM-223
HMGB1 Isoforms Kit - Test size	HM-030
Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells	HM-251
HMGB1 Isoforms Kit - Regular size	HM-031
20 ug p-mHMG1	HM-300
50 ug Terminally oxidized HMGB1, LPS free	HM-062
20 ug p-mHMG1tag	HM-301
100 ug Terminally oxidized HMGB1, LPS free	HM-061
20 ug pEGFP-HMGB1	HM-302
250 ug Terminally oxidized HMGB1, LPS free	HM-060
20 ug pcDNA/FL-RAGE plasmid	HM-310

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