• <nobr id="kxrth"></nobr>

    <center id="kxrth"></center>

    <pre id="kxrth"></pre>

        国产一本一道久久香蕉下载,亚洲男人的天堂视频,国产成人精品A视频,精品尤物TV福利院在线网站,欧美第一黄网免费网站,无码视频伊人,人人爽人人爽人人片a∨,中文字幕 日韩 人妻 无码
        您好!歡迎訪問上海起發實驗試劑有限公司網站!
        全國服務咨詢熱線:

        15921799099

        當前位置:首頁 > 產品中心 > > > Stemgent產品介紹

        Stemgent產品介紹

        簡要描述:美國Stemgent公司干細胞專家。它的宗旨是為生物科研工作者提供干細胞研究的試劑與試劑盒。 背景知識:干細胞是在動物體內存在的一種極特殊的細胞。這種細胞可以無窮盡的分裂,也可以變成或分化成體內各種組織器官的細胞。胚胎干細胞可以形成完整的胚胎或個體

        • 產品型號:
        • 廠商性質:代理商
        • 更新時間:2025-12-30
        • 訪  問  量:6052

        詳細介紹

        美國Stemgent公司干細胞專家。它的宗旨是為生物科研工作者提供干細胞研究的試劑與試劑盒。 背景知識:干細胞是在動物體內存在的一種極特殊的細胞。這種細胞可以無窮盡的分裂,也可以變成或分化成體內各種組織器官的細胞。胚胎干細胞可以形成完整的胚胎或個體。這就是個體克隆。Stemgent的宗旨是提供各種試劑與試劑盒,配備生物科研人員新的研究工具與手段。

        相關產品:
        Viruses 病毒
        Small Molecules 小分子
        Matrices 基質膠
        Cell Lines  細胞
        Antibodies / Biomarkers 抗體和標記物
        Cytokines 細胞因子
        Transfection 轉染試劑
        Primary Cells 原代細胞
        Media 培養基
         

        公司:https://www.stemgent.com

        Small Molecules
        Stemolecule™ Thiazovivin , Cat. No. 04-0017
        Stemolecule™ Thiazovivin dramatically improves the survival of hESCs upon trypsinization1. Thiazovivin in combination with inhibitors of the TGFβ receptor and the MEK pathway improve reprogramming efficiency more than 200-fold1.
        Stemolecule™ Rock II Inhibitor , Cat. No. 04-0030
        StemoleculeTM Rock II Inhibitor is a specific inhibitor for type 2 Rho-associated, coiled-coil containing protein kinase (Rock). Rock inhibitors have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency.
        Stemolecule™ Rock I Inhibitor , Cat. No. 04-0029
        Rock inhibitors, including Stemolecule™ Rock I Inhibitor, have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency.
        Stemolecule™ Cyclic Pifithrin-α , Cat. No. 04-0040
        Stemolecule™ Cyclic Pifithrin-α (Cyclic PFT-α) is a transcriptional inhibitor of p53. The reduction of p53 activity has been shown to enhance reprogramming efficiency of human and mouse somatic cells. Cyclic PFT-α sensitizes tumor cells to antimicrotubule agent induced apoptosis.
        Stemolecule™ Pifithrin-α , Cat. No. 04-0038
        Stemolecule™ Pifithrin-α (PFT-α) is a small molecule inhibitor of p53 dependent apoptosis and transcriptional activation for cyclin G, p21/waf1, and mdm2 expression. The reduction of p53 activity has been shown to enhance reprogramming efficiency of human and mouse somatic cells.
        Stemolecule™ BMP Inhibitor LDN-193189 , Cat. No. 04-0019
        StemoleculeTM BMP Inhibitor LDN-193189 functions primarily through inhibition of BMP type I receptors ALK2 and ALK3. LDN-193189 only weakly inhibits ALK4, ALK5, and ALK7. BMP signaling coordinates developmental patterning and has essential physiological roles in mature organisms.
        Stemolecule™ (-)-Indolactam V , Cat. No. 04-0020
        StemoleculeTM (-)-Indolactam V is a PKC isozyme inhibitor identified in a high-content chemical screen as a small molecule inducer of human embryonic stem cell differentiation to functional insulin-secreting beta cells at the definitive endoderm cell stage.
        Stemolecule™ SHH Antagonist , Cat. No. 04-0032
        StemoleculeTM SHH Antagonist is an inhibitor of Sonic hedgehog signaling (SHH). Hedgehog signaling is involved in embryogenesis as well as cancer progression. The mechanism for this antagonist is unknown.
        Stemolecule™ SMO Antagonist , Cat. No. 04-0031
        Stemolecule™ SMO Antagonist is an analog of SANT-2, an inhibitor of Sonic hedgehog signaling. Hedgehog signaling is involved in embryogenesis as well as cancer progression. The mechanism of action of SMO Antagonist is allosteric inhibition of Smoothened (SMO), an integral membrane protein mediator of Hedgehog signaling.
        Stemolecule™ Wnt Inhibitor IWP-4 , Cat. No. 04-0036
        Stemolecule™ Wnt Inhibitor IWP-4 is an antagonist of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity1. It blocks phosporylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.
        Stemolecule™ Wnt Inhibitor IWP-3 , Cat. No. 04-0035
        Stemolecule™ Wnt Inhibitor IWP-3 is an antagonist of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-3 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity1. It blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.
        Stemolecule™ Wnt Inhibitor IWP-2 , Cat. No. 04-0034
        Stemolecule™ Wnt Inhibitor IWP-2 is an antagonist of the Wnt/β-catenin pathway1. Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity1. It blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin1.
        Stemolecule™ IDE-2 , Cat. No. 04-0027
        Stemolecule™ IDE-2 is an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells in mouse and human ES cell cultures1. IDE-2 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.
        Stemolecule™ IDE-1 , Cat. No. 04-0026
        Stemolecule™ IDE-1 is an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells in mouse and human ES cell cultures. Endoderm chemically induced by IDE-1 can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.
        Stemolecule™ Doxycycline hyclate , Cat. No. 04-0016
        Stemolecule™ Doxycycline hyclate (Dox), a derivative of tetracycline, is used to induce expression of the Stemgent® iPSC Generation Dox Inducible products. In the iPSC Generation Dox Inducible protocol, addition of Dox to the culture medium of transduced cells induces the reverse tetracycline transactivator (rtTA) to bind to the Tet response element and results in the transcriptional activation for each of the factors implicated in the reprogramming process. Conversely, Dox can be removed from the medium to suppress transcriptional activation of the reprogramming factors.
        Stemolecule™ Forskolin , Cat. No. 04-0025
        Stemolecule™ Forskolin can potentiate neuron differentiation and can also stimulate adenylate cyclase activity and increase cyclic AMP. Protein kinase A (PKA) activity is dependent upon binding to cAMP and has been implicated in sonic hedgehog signaling.
        Stemolecule™ Dorsomorphin , Cat. No. 04-0024
        Dorsomorphin-2HCl is a potent inhibitor of AMP-activated protein kinase (AMPK) and bone morphogenic protein (BMP) signaling, functioning through inhibition of BMP type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation.
        Stemolecule™ Dexamethasone , Cat. No. 04-0023
        Stemolecule™ Dexamethasone is a glucocorticoid receptor agonist known to affect inflammatory responses, cellular proliferation, and differentiation in target tissues.
        Stemolecule™ Cyclopamine , Cat. No. 04-0022
        Stemolecule™ Cyclopamine has been identified as a specific inhibitor of hedgehog singaling by direct binding to the heptahelical bundle of Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. Cyclopamine has been utilized as a small molecule inducer of stem cell differentiation towards definitive endoderm pancreatic islet cells, as a modulator of cell proliferation, and as an anticancer drug.
        Stemolecule™ All-Trans Retinoic Acid , Cat. No. 04-0021
        Stemolecule™ All-Trans Retinoic Acid functions as a signaling molecule for various developmental pathways that control differentiation and proliferation. It has been used in various differentiation protocols, including B-cells, T cells and neurons, and implicated in specification of the embryonic anterior/posterior axis through Hox gene regulation.
        Stemolecule™ KAAD-Cyclopamine , Cat. No. 04-0028
        Stemolecule™ KAAD-Cyclopamine is a sonic hedgehog antagonist known to target Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. KAAD-Cyclopamine has been utilized to halt the migration or proliferation of a variety of cancer cells.
        iPSC Generation
        Stemolecule™ Tranylcypromine hydrochloride , Cat. No. 04-0033
        Stemolecule™ Tranylcypromine inhibits BHC110/LSD1, a histone H3 lysine 4 demethylation enzyme with close homology to monoamine oxidases. Treatment of P19 embryonal carcinoma cells with tranylcypromine resulted in global increase in H3K4 methylation as well as transcriptional derepression of the pluripotent stem cell marker Oct4.
        Kits / Sets
        Stemolecule™ MAPK Signaling Pathway Modulator Set , Cat. No. 00-0041
        The Stemolecule™ MAPK Signaling Pathway Modulator Set consists of three cell-permeable small molecules: PD0325901, PD173074, and SC1 (Pluripotin), which can modulate the MAPK signaling cascade. PD0325901 is a MEK inhibitor; PD173074 is an ATP-competitive inhibitor of the FGF receptor, known to activate the MAPK/ERK cascade; and SC1 (Pluripotin) acts through dual inhibition of ERK 1 and Ras-GAP. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.
        Stemolecule™ iPS Cell Enhancer Set , Cat. No. 00-0040
        The Stemolecule™ iPS Cell Generation Enhancer Set is a proven set of small molecules designed to improve iPS cell generation efficiency. The set consists of four cell-permeable small molecules: RG108, BIX1294, Valproic Acid (VPA), and R(+)Bay K 8644.
        Stemolecule™ Epigenetic Modifier Set , Cat. No. 00-0039
        The Stemolecule™ Epigenetic Modifier Set is a complete set of small molecules for modulating epigenetic effects of DNA and histones. The set consists of four cell-permeable small molecules: BIX01294, Sodium Butryate, RG108, and Valproic Acid (VPA). BIX01294 is a selective inhibitor of G9a HMTase, Sodium Butryate is an inhibitor of histone deacetylases, RG108 is a DNA methyltransferase inhibitor, and VPA is an inhibitor of histone deacetylases. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.
        Stemolecule™ TGF-beta Signaling Pathway Modulator Set , Cat. No. 00-0038
        The Stemolecule™ TGF-β Small Molecule Set is an inclusive set of small molecules for regulating the transforming growth factor beta (TGF -β) signaling pathway. The set consists of three Stemolecules™, SB431542, A83-01, and ALK5 Inhibitor: activin receptor-like kinase (ALK) receptors that work as TGF-β. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.
        Components
        Stemolecule™ ALK5 Inhibitor , Cat. No. 04-0015
        ALK5 Inhibitor is a potent small molecule that selectively inhibits the TGF-β signaling pathway.
        Stemolecule™ A83-01 , Cat. No. 04-0014
        A83-01 is a potent small molecule that selectively inhibits ALK4, ALK5, and ALK7 receptors. This small molecule has been used to generate rat and human iPS cells towards a mouse ES cell like self-renewal state.
        Stemolecule™ BIO , Cat. No. 04-0003
        BIO is the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells.1
        Stemolecule™ CHIR99021 , Cat. No. 04-0004
        CHIR99021 is the most selective inhibitor of GSK3β.
        Stemolecule™ Sodium Butyrate , Cat. No. 04-0005
        In cultured mouse and human cells, sodium butyrate has been shown to inhibit both the mRNA and protein content of cyclin D1.1 Sodium butyrate is a known inhibitor of histone deacetylases.2
        Stemolecule™ Purmorphamine , Cat. No. 04-0009
        Stemolecule™ Purmorphamine promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts.1,2 It is ideal for stem cell and cell signaling researchers using human embryonic stem cells to investigate differentiation with small molecules.
        Stemolecule™ SB431542 , Cat. No. 04-0010
        SB431542 has been shown to stimulate proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells via ALK receptor inhibition.1,2
        iPSC Generation Components
        Stemolecule™ PD173074 , Cat. No. 04-0008
        PD173074 inhibits the FGF signaling pathway.
        Stemolecule™ Valproic Acid , Cat. No. 04-0007
        VPA has been shown to enhance iPS generation in a three-factor transduction (Oct4, Klf4 and Sox2) without introduction of the c-Myc oncogene.1
        Stemolecule™ PD0325901 , Cat. No. 04-0006
        PD0325901 selectively binds and inhibits MEK, which may result in the inhibition of the phosphorelation and activation of MAPK/ERK.1,2
        Stemolecule™ SC1 (Pluripotin) , Cat. No. 04-0011
        SC1 (Pluripotin) is a high-quality, affordable small molecule LIF replacement for mouse embryonic (mES) cell self-renewal. SC1 maintains mES cells in an undifferentiated self-renewal state in the absence of LIF, feeder cells, or serum.
        Stemolecule™ Y27632 , Cat. No. 04-0012
        Y27632 is a Rho-associated kinase ROCK inhibitor that enhances survival and cloning efficiency of human embryonic stem cells.
        Stemolecule™ R(+)Bay K 8644 , Cat. No. 04-0013
        R(+)Bay K 8644 is a small molecule that enhances reprogramming efficiency when used with BIX01294.
        Stemolecule™ BIX01294 , Cat. No. 04-0002
        BIX01294 enhances reprogramming efficiency of neural progenitor cells to the same levels as when four transcription factors (Oct4, Klf4, Sox2 and c-Myc) were introduced to somatic cells.1,2
        Stemolecule™ RG108 , Cat. No. 04-0001
        Stemolecule™ RG108 is the highest purity preparation available, only from Stemgent. RG108 is a cell-permeable, specific DNA methyltransferase inhibitor that displays anti-proliferative properties with no detectable cytotoxic effects.1

        產品咨詢

        留言框

        • 產品:

        • 您的單位:

        • 您的姓名:

        • 聯系電話:

        • 常用郵箱:

        • 省份:

        • 詳細地址:

        • 補充說明:

        • 驗證碼:

          請輸入計算結果(填寫阿拉伯數字),如:三加四=7
        上海起發實驗試劑有限公司
        地址:上海浦東川沙鎮川沙路6619號上海起發實驗試劑有限公司
        郵箱:xs1@78bio.com
        傳真:021-50724961
        關注我們
        歡迎您關注我們的微信公眾號了解更多信息:
        歡迎您關注我們的微信公眾號
        了解更多信息
        主站蜘蛛池模板: 亚洲综合一区二区三区蜜臀av| 国产精品黑人一区二区三区| 久久久噜噜噜久久| 亚洲精品中文字幕一区二| 亚洲中文无码永久免| 超碰国产精品久久国产精品99| 亚洲精品无码视频| 一区二区三区无码免费看| 免费a级毛片18以上观看精品| 无码专区人妻系列日韩精品少妇| 国产放荡av剧情演绎麻豆| 久久99国产伦精品免费| 欧美乱强伦xxxx孕妇| 中文字幕日本人妻一区| 999久久66久6只有精品| 97人人模人人爽人人喊电影| 色窝窝无码一区二区三区| 亚洲中文精品久久久久久| 野外性史欧美k8播放| 日本人妻中文字幕乱码系列| 播播四房| 日韩欧美中文字幕在线观看 | 乱码1/2| 起碰免费公开97在线视频| 欧美牲交a欧美牲交| 亚洲中文字幕一二三四区| 色欲AV成人无码精品无码| 亚洲精品一区二区制服| (原创)露脸自拍[62p]| 国产精品无码无在线观看| 国产真人无遮挡免费视频| 国产91精品丝袜美腿在线| 国产精品久久婷婷婷婷| 欧美最猛性xxxxx69| 国产又色又爽无遮挡免费| 在线免费不卡视频| 日韩中文字幕不卡在线| 深夜福利av无码一区二区| 日韩欧美第一区二区三区| 亚洲国产欧美中文丝袜日韩| 亚洲精品午夜久久久伊人|